More than traders in their area the Huron received Roman Catholic missionaries to Huronia. Catholicism then went running rampant over the Huron people, as this happened European illnesses went like wild fire over Huronia.
http://www.catholichistory.net/images/Father_marquette_preaching.jpg
One thing that can be found to assist in the fall of the Huron people is the continuing animosity between the original native people of the area that was brought on by the continuing interference of the European people. In the early 18th century there began three major wars that effected the connection between Huron and the European new comers. The Spainish Succession (1702-1713), the Austrian Succession (1744-1748) and the Seven Years War (1754-17630) caused for the native people to have to choose a side and pick wether they would be against the new rulers, the French, or join them in the conquest of the northern part of North America.
http://www.cmhg-phmc.gc.ca/cmh/book_images/high/v1_c3_s03_ss00_01.jpg
